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KMID : 0370219960400010046
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Yakhak Hoeji
1996 Volume.40 No. 1 p.46 ~ p.51
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Synthesis of D-1,3-Dioxolane and L-1,3-Oxathiolane 5-Phenylselenyl Pyrimidine Nucleosides as Potential Antiviral Agents
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유정만/Yoo JM
문현주/정병호/최보길/홍준희/천문우/Moon HJ/Chung BH/Choi BG/Hong JH/Chun MW
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Abstract
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Eight new D-1.3-dioxolanyl and L-1,3-oxathiolanyl nucleosides containing 5-phenyl- selenyl pyrimidine bases which are expected to have antiviral activity were synthesized. Condensation of D-1,3-dioxolane acetate and L-1,3-oxathiolane acetate with 5-phenylselenyl pyrimidines gave anomeric mixtures of their nucleosides which were separated by silicagel column chromatography.
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